The location you need to head to is: The Last Bookstore

The final word of the specified book title is: River

The location you need to head to is: Angels Flight Railway

Using the cipher, you can unscramble the clue to see that it asks you to: Find the plaque at the top of the hill.

The fifth word on the second to last line of the plaque is: golden

The location you need to head to is: Griffith Observatory

Using the match, you can put heat near the paper to reveal the question: who stands to the right of Hipparchus?

The name of the figure on the monument to the right of Hipparchus is: Herschel

The location you need to head to is: TCL Chinese Theatre

Using the cipher, you can unscramble the clue to see that it asks you to: Find Tom Hank's hand and footprints.

The month that his hand and footprints were cemented there is: July

The location you need to head to is: Pacific Park at Santa Monica Pier

Using the decoder glasses, you can see that the paper asks you to: Find the Shark Frenzy ride

The number of teeth on each shark is: twenty

On the answer sheet, if you take the letters from the clue answers that are in a square you get:

On the list of codes, the phrase is associated with the 3 digit combination: which will unlock the chest